Dr. Yue Zhou

Boya Junior Researcher

Plant Chromatin Status Research Group
State Key Laboratory for Protein and Plant Gene Research
School of Advanced Agricultural Sciences
Peking-Tsinghua Center for Life Sciences
Peking University

Email: yue_zhou@pku.edu.cn

Research Area

Chromatin 3D structure, Plant epigenetics

Short Bio

Yue Zhou, Ph.D in Cell Biology from the Lanzhou University and National Institute of Biological Sciences, holds the Boya Junior Researcher at Peking University and is a researcher at the State Key Laboratory for Protein and Plant Gene Research and Peking-Tsinghua Center for Life Sciences. His lab overarching research interests focuses on the role of epigenetic regulation in plant development. He uses combined genetics, genomics, cell biology and biochemistry approaches to study the molecular mechanism of plant chromatin 3D structure regulation, and how chromatin 3D structure is able to affect transcription and genome maintenance. Dr. Zhou has published 17 papers in peer-reviewed journals, including Science, Nature Genetics, Nature Communications, PNAS, Plant Cell, etc.

Selected Publications

1.  Yin, X., Romero-Campero, F JM., Yang, M., Baile, F., Cao, Y., Shu, J., Luo, L., Wang, D., Sun, S., Yan, P., Gong, Z., Mo, X., Qin, G., Myriam, C#, Zhou, Y^#. (2023). Binding by the Polycomb complex component BMI1 and H2A monoubiquitination shape local and long-range interactions in the Arabidopsis genome. Plant Cell 35, 2484-2503. 10.1093/plcell/koad112.

2.  Yang, T.T., Wang, D.Y., Tian, G.M., Sun, L.H., Yang, M.Q., Yin, X.C., Xiao, J., Sheng, Y., Zhu, D.M., He, H., and Zhou, Y. (2022). Chromatin remodeling complexes regulate genome architecture in Arabidopsis. Plant Cell 34, 2638-2651. 10.1093/plcell/koac117.

3.  Wei, S.B., Li, X., Lu, Z.F., Zhang, H., Ye, X.Y., Zhou, Y.J., Li, J., Yan, Y.Y., Pei, H.C., Duan, F.Y., Wang D.Y., Song, C., Wang, P., Zhang, C., Shang, L.G., Zhou, Y., Yan, P., Zhao, M., Huang J.R., Bock, R., Qian, Q., Zhou W.B. (2022). A transcriptional regulator that boosts grain yields and shortens the growth duration of rice. Science 377, eabi8455. 10.1126/science.abi8455.

4.  Gao, Z., Zhou, Y., and He, Y. (2022). Molecular epigenetic mechanisms for the memory of temperature stresses in plants. J Genet Genomics 49, 991-1001. 10.1016/j.jgg.2022.07.004.

5.  Yin, X., Romero-Campero, F.J., de Los Reyes, P., Yan, P., Yang, J., Tian, G., Yang, X., Mo, X., Zhao, S., Calonje, M., and Zhou, Y. (2021). H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots. Nat Commun 12, 315. 10.1038/s41467-020-20614-1.

6.  Lan, J., Zhang, J., Yuan, R., Yu, H., An, F., Sun, L., Chen, H., Zhou, Y., Qian, W., He, H., and Qin, G. (2021). TCP Transcription Factors Suppress Cotyledon Trichomes by Impeding a Cell Differentiation-regulating Complex. Plant Physiol 186, 434-451. 10.1093/plphys/kiab053.

7.  Zhou, Y., Wang, Y., Krause, K., Yang, T., Dongus, J.A., Zhang, Y., and Turck, F. (2018). Telobox motifs recruit CLF/SWN-PRC2 for H3K27me3 deposition via TRB factors in Arabidopsis. Nat Genet 50, 638-644. 10.1038/s41588-018-0109-9.

8.  Xue, L., Klinnawee, L., Zhou, Y., Saridis, G., Vijayakumar, V., Brands, M., Dormann, P., Gigolashvili, T., Turck, F., and Bucher, M. (2018). AP2 transcription factor CBX1 with a specific function in symbiotic exchange of nutrients in mycorrhizal Lotus japonicus. Proc Natl Acad Sci U S A 115, E9239-E9246. 10.1073/pnas.1812275115.

9.  Cui, H., Qiu, J., Zhou, Y., Bhandari, D.D., Zhao, C., Bautor, J., and Parker, J.E. (2018). Antagonism of transcription factor MYC2 by EDS1/PAD4 complexes bolsters salicylic acid defense in Arabidopsis effector-triggered immunity. Mol Plant 11, 1053-1066. 10.1016/j.molp.2018.05.007.

10. Zhou, Y., Tergemina, E., Cui, H., Forderer, A., Hartwig, B., Velikkakam James, G., Schneeberger, K., and Turck, F. (2017). Ctf4-related protein recruits LHP1-PRC2 to maintain H3K27me3 levels in dividing cells in Arabidopsis thaliana. Proc Natl Acad Sci U S A 114, 4833-4838. 10.1073/pnas.1620955114.

11. Zhou, Y., Romero-Campero, F.J., Gomez-Zambrano, A., Turck, F., and Calonje, M. (2017). H2A monoubiquitination in Arabidopsis thaliana is generally independent of LHP1 and PRC2 activity. Genome Biol 18, 69. 10.1186/s13059-017-1197-z.

12. Merini, W., Romero-Campero, F.J., Gomez-Zambrano, A., Zhou, Y., Turck, F., and Calonje, M. (2017). The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development. Plant Physiol 173, 627-641. 10.1104/pp.16.01259.

13. Zhou, Y., Hartwig, B., James, G.V., Schneeberger, K., and Turck, F. (2016). Complementary Activities of TELOMERE REPEAT BINDING Proteins and Polycomb Group Complexes in Transcriptional Regulation of Target Genes. Plant Cell 28, 87-101. 10.1105/tpc.15.00787.

14. Förderer, A., Zhou, Y., and Turck, F. (2016). The age of multiplexity: recruitment and interactions of Polycomb complexes in plants. Curr Opin Plant Biol 29, 169-178. 10.1016/j.pbi.2015.11.010.

15. Hu, J.-Y., Zhou, Y., He, F., Dong, X., Liu, L.-Y., Coupland, G., Turck, F., and de Meaux, J. (2014). miR824-Regulated AGAMOUS-LIKE16 Contributes to Flowering Time Repression in Arabidopsis. Plant Cell 26, 2024-2037. 10.1105/tpc.114.124685.

16. Zhou, Y., Zhang, J., Lin, H., Guo, G., and Guo, Y. (2010). MORPHEUS' MOLECULE1 is required to prevent aberrant RNA transcriptional read-through in Arabidopsis. Plant Physiol 154, 1272-1280. 10.1104/pp.110.162131.

17. Zhou, Y., Yang, Z., Guo, G., and Guo, Y. (2010). Microfilament dynamics is required for root growth under alkaline stress in Arabidopsis. J Integr Plant Biol 52, 952-958. 10.1111/j.1744-7909.2010.00981.x.