Dr. Yue Zhou

Boya Junior Researcher

Plant Chromatin Status Research Group
State Key Laboratory for Protein and Plant Gene Research
School of Advanced Agricultural Sciences
Peking-Tsinghua Center for Life Sciences
Peking University

Email: yue_zhou@pku.edu.cn

Research Area

Epigenetic and plant development.

Short Bio

Yue Zhou, Ph.D in Cell Biology from the Lanzhou University and National Institute of Biological Sciences, holds the Boya Junior Researcher at Peking University and is a researcher at the State Key Laboratory for Protein and Plant Gene Research and Peking-Tsinghua Center for Life Sciences. His lab overarching research interests focuses on the role of epigenetic regulation in plant development. He uses combined genetics, genomics, cell biology and biochemistry approach to study the molecular mechanism of histone modification and 3D chromatin regulation, and how epigenetic is able to affect transcription and plant development. Dr. Zhou has published 25 papers in peer-reviewed journals, including Molecular Cell, Nature Genetics, Nature Communications, PNAS, Plant Cell, etc.

Publications

Luo, L., Yang, M., and Zhou, Y. (2025). BMI1s interact with condensin complexes to regulate chromatin 3D structure and gene expression in Arabidopsis. aBIOTECH, https://doi.org/10.1007/s42994-025-00202-x.

Song, Z., Xia, Q., Yang, M., Yang, T., Liu, Y., Wang, D., Shu, J., Liu, Z., Chi, Y., Xu, H., Xing, D., and Zhou, Y. (2025). Dynamic changes in 3D chromatin structure during male gametogenesis in Arabidopsis thaliana. Genome Biol 26, 27.

Wang, D., Xiao, S., Shu, J., Luo, L., Yang, M., Calonje, M., He, H., Song, B., and Zhou, Y. (2024). Promoter capture Hi-C identifies promoter-related loops and fountain structures in Arabidopsis. Genome Biol 25, 324.

Shu, J., Sun, L., Wang, D., Yin, X., Yang, M., Yang, Z., Gao, Z., He, Y., Calonje, M., Lai, J., Deng, X.W., He, H., and Zhou, Y. (2024). EMF1 functions as a 3D chromatin modulator in Arabidopsis. Mol Cell 84, 4729-4739 e4726.

Yang, T.T., Wang, D.Y., Luo, L.X., Yin, X.C., Song, Z.H., Yang, M.Q., and Zhou, Y. (2024). PWOs repress gene transcription by regulating chromatin structures in Arabidopsis. Nucleic Acids Research.

Yin, X., Romero-Campero, F.J., Yang, M., Baile, F., Cao, Y., Shu, J., Luo, L., Wang, D., Sun, S., Yan, P., Gong, Z., Mo, X., Qin, G., Calonje, M., and Zhou, Y. (2023). Binding by the Polycomb complex component BMI1 and H2A monoubiquitination shape local and long-range interactions in the Arabidopsis genome. Plant Cell 35, 2484-2503.

Yang, T.T., Wang, D.Y., Tian, G.M., Sun, L.H., Yang, M.Q., Yin, X.C., Xiao, J., Sheng, Y., Zhu, D.M., He, H., and Zhou, Y. (2022). Chromatin remodeling complexes regulate genome architecture in Arabidopsis. Plant Cell 34, 2638-2651.

Yin, X., Romero-Campero, F.J., de Los Reyes, P., Yan, P., Yang, J., Tian, G., Yang, X., Mo, X., Zhao, S., Calonje, M., and Zhou, Y. (2021). H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots. Nat Commun 12, 315.

Zhou, Y., Wang, Y., Krause, K., Yang, T., Dongus, J.A., Zhang, Y., and Turck, F. (2018). Telobox motifs recruit CLF/SWN-PRC2 for H3K27me3 deposition via TRB factors in Arabidopsis. Nat Genet 50, 638-644.

Zhou, Y., Romero-Campero, F.J., Gomez-Zambrano, A., Turck, F., and Calonje, M. (2017a). H2A monoubiquitination in Arabidopsis thaliana is generally independent of LHP1 and PRC2 activity. Genome Biol 18, 69.

Zhou, Y., Tergemina, E., Cui, H., Forderer, A., Hartwig, B., Velikkakam James, G., Schneeberger, K., and Turck, F. (2017b). Ctf4-related protein recruits LHP1-PRC2 to maintain H3K27me3 levels in dividing cells in Arabidopsis thaliana. Proc Natl Acad Sci U S A 114, 4833-4838.

Zhou, Y., Hartwig, B., James, G.V., Schneeberger, K., and Turck, F. (2016). Complementary Activities of TELOMERE REPEAT BINDING Proteins and Polycomb Group Complexes in Transcriptional Regulation of Target Genes. Plant Cell 28, 87-101.